Summary information and primary citation
- PDB-id
-
190d;
SNAP-derived features in text and
JSON formats
- Class
- DNA
- Method
- X-ray (1.8 Å)
- Summary
- Crystal structure of a four-stranded intercalated DNA:
d(c4)
- Reference
-
Chen L, Cai L, Zhang X, Rich A (1994): "Crystal
structure of a four-stranded intercalated DNA:
d(C4)." Biochemistry, 33,
13540-13546. doi: 10.1021/bi00250a005.
- Abstract
- The crystal structure of d(C4) solved at 2.3-A
resolution reveals a four-stranded molecule composed of two
interdigitated or intercalated duplexes. The duplexes are
held together by hemiprotonated cytosine-cytosine base
pairs and are parallel stranded, but the two duplexes point
in opposite directions. The molecule has a slow
right-handed twist of 12.4 degrees between covalently
linked cytosine base pairs, and the base stacking distance
is 3.1 A. This is in general agreement with the NMR
studies. A biological role for DNA in this conformation is
suggested.
